By the mid-1990s trance, specifically Progressive trance, which emerged from acid trance much as Progressive house had emerged from Acid house, had emerged commercially as one of the dominant genres of dance music. Progressive trance has set in stone the basic formula of modern trance by becoming even more focused on the anthemic basslines and lead melodies, moving away from hypnotic, repetitive, arpeggiated analog synth patterns and spacey pads. Popular elements and anthemic pads became more widespread. Compositions leaned towards incremental changes (aka progressive structures), sometimes composed in thirds (as BT frequently does). Meanwhile, a different type of trance, generally called uplifting trance was becoming popular. Uplifting trance had buildups and breakdowns that were longer and more exaggerated, being more direct and less subtle than progressive, with more easily identifiable tunes and anthems. Many such trance tracks follow a set form, featuring an introduction, steady build, a breakdown, and then an anthem, a form aptly called the "build-breakdown-anthem" form. Uplifting vocals, usually female, were also becoming more and more prevalent, adding to trance's popular appeal.

Immensely popular, trance found itself filling a niche that was 'edgier' than house, more soothing than drum and bass, and more melodic than techno, which made it accessible to a wider audience. Artists like Tiësto, Armin van Buuren, Paul van Dyk, Robert Miles, Above & Beyond, Darren Tate, Ferry Corsten, Johan Gielen, ATB and Paul Oakenfold came to the forefront as premier producers and remixers, bringing with them the emotional, "epic" feel of the style. Many of these producers also DJ'd in clubs playing their own productions as well as those by other trance DJs. By the end of the 1990s, trance remained commercially huge, but had fractured into an extremely diverse genre. Some of the artists that had helped create the trance sound in the early and mid-1990s had, by the end of the decade, abandoned trance completely in favor of more underground sounds - artists of particular note here include Pascal F.E.O.S. and Oliver Lieb.

As trance entered the mainstream it alienated many of its original fans. As the industry became bigger, record labels, Ibiza based producers, clubs (most notably Ministry of Sound) and DJs began to alter their sound to more of a pop based one, so as to make the sound more accessible to an even wider, and younger, audience.

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